Process for the preparation of optically active ortho-substitute

Details Process for the preparation of optically active ortho-substitute Process for the preparation of optically active ortho-substitute

1996-08-26

1998-01-13

Davis, Zinna Northington

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

5462694, 5462804, 5462837, 546286, 546304, 546326, 546327, C07D21182, C07D21184, C07D40104, C07D40904

Patent

active

057081778

ABSTRACT:
The invention relates to a process for the preparation of optically active ortho-substituted 4-aryl- or heteroaryl-1,4-dihydropyridines by oxidation and subsequent reduction from their opposite enantiomers.

REFERENCES:
patent: 3954737 (1976-05-01), Rinehart, Jr. et al.
patent: 4988717 (1991-01-01), Wehinger et al.
patent: 5288928 (1994-02-01), Broger et al.
patent: 5374727 (1994-12-01), Broger
patent: 5481008 (1996-01-01), Broger et al.
S. Goldmann, et al., Angew Chm. Int. Ed. Eng., vol. 30, pp. 1559-1578 (1991).
Database WPI, AN 91-263838, Abstract of JP 03-173869, (1991).
M. Hudlick, "Reductions in Organic Chemistry" pp. 4-24, John Wilegt Sons, New York (1984).

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