RNA-DNA hybrid molecules of nucleic acid

Details RNA-DNA hybrid molecules of nucleic acid RNA-DNA hybrid molecules of nucleic acid

1991-08-16

1998-01-13

Wilson, James O.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 435 75, 435 911, 435 9151, 536 221, 536 253, 536 2532, 536 2534, C07H 2100, C12Q 168

Patent

active

057081549

ABSTRACT:
Molecules having an RNA block linked to a shorter DNA block is described. The RNA and DNA blocks are complementary to accommodate formation of fold-back molecules having a 3' hydroxyl on the DNA block and an overhanging RNA strand at the end of a short DNA-RNA hybrid.

REFERENCES:
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patent: 4794073 (1988-12-01), Dattagupta et al.
patent: 4859768 (1989-08-01), Suhaddnik et al.
patent: 5011769 (1991-04-01), Duck et al.
patent: 5047519 (1991-09-01), Hobbs, Jr. et al.
patent: 5215899 (1993-06-01), Dattagupta et al.
Alberts et al., The Molecular Biology of the Cell, pp. 188-190, 1983.

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