KS-501 derivatives

Details KS-501 derivatives KS-501 derivatives

1989-09-15

1991-04-02

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 41, 536115, 514 25, 514532, 514533, 514544, C07H 1500, A61K 31715

Patent

active

050048333

ABSTRACT:
Disclosed are KS-501 derivatives represented by the formula (I) ##STR1## wherein X represents a hydrogen atom or COOR.sub.3, Y represents hydroxy or ##STR2## and R.sub.1, R.sub.2 and R.sub.3 are the same or different and represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, provided that when R.sub.1, R.sub.2 and R.sub.3 are simultaneously hydrogen atoms, and when R.sub.1, R.sub.2 and X are simultaneously hydrogen atoms, Y does not represent ##STR3## and a pharmaceutically acceptable acid addition salt thereof. The KS-501 derivatives have a platelet aggregation-inhibiting property, and are expected to be useful as antithrombotic agent.

REFERENCES:
patent: 4801697 (1989-01-01), Yaginuma et al.
Prostaglandins, vol. 24, No. 1, pp. 21-34 (Jul. 1981).
Chemical Abstracts, vol. 102, No. 9, Abstract No. 75671c (1985).
Chemical Abstracts, vol. 107, No. 1, Abstract No. 4264q (1987).
Chemical Abstracts, vol. 111, No. 3, Abstract No. 20565b (1989).
Chem. Pharm. Bull., vol. 28, 3157-3162 (1980).
J. Antibiot, vol. 37, 469-474 (1984).
J. Antibiot, vol 37, 1153-1160 (1984).
Agric. Biol. Chem., vol. 50, 2723-2727 (1986).

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