Substituted propane-phosphonous acid compounds

Details Substituted propane-phosphonous acid compounds Substituted propane-phosphonous acid compounds

1989-12-01

1991-04-02

Evans, J. E.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

558166, 558170, 502 11, 502 15, C07F 930, C07F 932

Patent

active

050048260

ABSTRACT:
The compounds of the formula ##STR1## in which one of the groups R.sup.1, R.sup.2 and R.sup.3 represents hydrogen, C.sub.1-8 -alkyl, C.sub.3-6 -cycloalkyl, phenyl optionally substituted by halogeno, C.sub. 1-4 -alkyl, C.sub. -4 -alkoxy and/or trifluoromethyl, or C.sub.7-10 -phenylalkyl optionally substituted in the phenyl moiety by halogeno, C.sub.1-4 -alkyl C.sub.1-4 -alkoxy and/or trifluormethyl, and the other two are hydrogen, or salts thereof.
These compounds have valuable pharmaceutical properties.

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Enna, et al. J. Med. Chem. 27, 654 (1984).
Aust. J. Chem. 33, 292 (1980).
Kreutckamp et al "Chem Abstracts" vol. 57 (1962) cols. 5046 and 5947.

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