High blood pressure relief method and compositions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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562553, A61K 31195, C07C22906

Patent

active

057080291

ABSTRACT:
Disclosed is the method of determining the effectiveness of an agent for the relief of elevation of the blood pressure, comprising the steps of

REFERENCES:
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Murray, R.H.: Blood Pressure Responses to Extreme Sodium Intake in Normal Man. Proc. Soc. Exp. Biol. Med. vol. 159, pp. 432-436, 1978.
Zandberg, P.: Animal Models in Experimental Hypertension: Relevance to Drug Testing and Discovery. Handbook of Hypertension, vol. 3, pp. 1-33, 1984.
Patel, A. et al.: L-Arginine Administration Normalizes Pressure Natriuresis in Hypertensive Dahl Rats. Hypertension, vol. 22, pp. 863-869, 1993.
Tsuji et al.: Antihypertensive Activities of Benikoji
Extracts and Gama-Aminobutyric Acid in Spontaneously Hypertensive Rats. Eiyogaku Zasshi, vol. 50, pp. 285-291, 1992.
Ohnuki, N. et al.: Effects of L-Cysteine on Blood Pressure in Hypertensive Rats and Some Aspects of its mechanism. yakasi to Chiryo, vol. 15, pp. 1195-1201, 1987.
Tobian, L.: NaCl-Related Hypertensions. Hypertension Edited by Ong and Lewis, pp. 96-97 and 115, 1984.

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