Retroviral protease inhibitors

Details Retroviral protease inhibitors Retroviral protease inhibitors

1992-04-29

1996-04-16

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546165, 546153, 514311, 514312, 514313, 514314, C07D21548, A61K 3147

Patent

active

055084079

ABSTRACT:
The present invention provides novel HIV protease inhibitors, pharmaceutical formulations containing those compounds and methods of their use.

REFERENCES:
Roberts, N. A. et al, Science, 248, 358-361 (1990).
Tam, T. F. et al., Journal of Medicinal Chemistry, 35(7), 1318-1320 (3 Apr. 1992).
Young, S. G., et al., Journal of Medicinal Chemistry, 35(10), 1702-1709 (15 May 1992).
Huff, J. R., Journal of Medicinal Chemistry, 34(8), 2305-2314 (Aug. 1991).
Snieckus, Chemical Reviews, 90, 879-933 (1990).
Beak, et al., Tetrahedron, 39, 1983-1989 (1983).
Nahm and Weinreb, Tetrahedron Letters, 22, 3815-3818 (1981).
Fehrentz and Castro, Synthesis, No. 8, 676-678 (1983).

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