Diagnosis of Mycobacterium bovis infection

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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4241901, 436811, 530395, 530820, G01N 33554, A61K 3902, C07K 1435

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active

057078190

ABSTRACT:
A method for the diagnosis of Mycobacterium bovis infection in a susceptible animal, comprises detection in said animal of antibodies against the MPB-70 protein of M.bovis and/or the detection of a cell-mediated immune response of said animal to the said MPB-70 protein. Also disclosed is a recombinant DNA molecule corresponding to all or portion of the M.bovis DNA sequence coding for the MPB-70 protein or a polypeptide having the antigenicity of MPB-70 protein, or degenerate forms thereof, as well as recombinant MPB-70 protein or polypeptide and a process for the preparation thereof.

REFERENCES:
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