Isolated RAGE-1 derived peptides which complex with HLA-B7 molec

Details Isolated RAGE-1 derived peptides which complex with HLA-B7 molec Isolated RAGE-1 derived peptides which complex with HLA-B7 molec

1995-09-20

1999-08-17

Schwadron, Ronald B.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

8 to 10 amino acid residues in defined sequence

530300, 530350, 530828, 530395, 514 15, 514 2, 514885, 4241841, 4241851, 4242771, C07K 700, C07K 706, A61K 3808, A61K 3804

Patent

active

059395265

ABSTRACT:
The invention describes the RAGE tumor rejection antigen precursor family, including nucleic acids encoding such tumor rejection antigen precursors, tumor rejection antigen peptides or precursors thereof and antibodies relating thereto. Methods and products also are provided for diagnosing and treating conditions characterized by expression of a RAGE tumor rejection antigen precursor.

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patent: 5405940 (1995-04-01), Boon et al.
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Schendel et al., Tumor-Specific Lysis of Human Renal Cell Carcinomas by Tumor-Infiltrating Lymphocytes, J. Immunology 151:4209-4220, 1993.
Van den Eynde et al., New tumor antigens recognized by T cells. Curr. Opinion in Immun. 7:674-681, 1995.
Choudhary et al., Selective lysis of autologous tumor cells by recurrent .gamma..delta. tumor-infiltrating lymphocytes from renal carcinoma. J. Immunol. 154: 3932, 1995.
Van den Eynde et al., Presence on a Human Melanoma of Multiple Antigens Recognized by Autologous Ctl. Int. J. Cancer:44, 634-640, 1989.
Rammensee, et al., MHC ligands andpeptide motifs: first listing. Immunogenetics 41: 178-228, 1995.

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