Use of naphthalene derivatives in treating lung carcinoma

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514255, 514256, A61K 31495, A61K 3150

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active

058212450

ABSTRACT:
A method of inhibiting cell growth in human small cell lung carcinoma comprising administering to a mammal in need of such treatment a cell growth inhibitory amount of a compound of the formula ##STR1##

REFERENCES:
Cattaneo, Maria G., et al., "Mitogenic effect of serotonin in human cell lung carcinoma cells", European Journal of Pharmacology, Molecular Pharmacology Section 291, pp. 209-211 (1995).
Cattaneo, Maria G., et al., "5-HT.sub.1D receptor type is involved in stimulation of cell proliferation by serotonin in human small cell lung carcinoma", European Journal of Pharmacology, Molecular Pharmacology Section 268, pp. 425-430 (1994).
Ishibashi, Miyuki, et al., "Inhibition of Growth of Human Small Cell Lung Cancer by Bromocriptine", Cancer Research, 54, pp. 3442-3446, Jul. 1, 1994 .

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