Method for the treatment of corticosteroid induced osteopenia co

Details Method for the treatment of corticosteroid induced osteopenia co Method for the treatment of corticosteroid induced osteopenia co

1995-06-07

1998-10-13

Kemmerer, Elizabeth C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 514 8, 514 13, 514 14, 514 15, 514 16, 514 17, 514 18, 514 19, 435 691, A61K 3829, A61K 3816

Patent

active

058212256

ABSTRACT:
Synthetic polypeptide analogs of parathyroid hormone PTH, parathyroid hormone related peptide PTHrp, and of the physiologically active truncated homologs and analogs of PTH and PTHrp, in which amino acid residues (22-31) form an amphipathic .alpha.-helix, said residues (22-31) selected from hydrophilic amino acids (Haa) and lipophilic amino acids (Laa) ordered in the sequence:

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patent: 5317010 (1994-05-01), Pang et al.
patent: 5382658 (1995-01-01), Kronis et al.
patent: 5393869 (1995-02-01), Nakagawa et al.
patent: 5434246 (1995-07-01), Fukuda et al.
Bowie et al. Science 247:1306-1310, 1990.
Adachi, et al., "Corticosteroid-Induced Osteoporosis", Semin. Arthritis Rheum., 22:6 (1993) pp. 375-384.

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