Phospholipase A.sub.2 inhibitors

Details Phospholipase A.sub.2 inhibitors Phospholipase A.sub.2 inhibitors

1995-05-08

1996-01-16

McKane, Joseph K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548540, A61K 31395, C07D20722

Patent

active

054848067

ABSTRACT:
There are disclosed compounds of the formula: ##STR1## wherein R.sup.1 is hydrogen, alkyl, cycloalkyl, arylalkyl, --(CH.sub.2).sub.r CH.dbd.CH.sub.2, --(CH.sub.2).sub.s OY, --(CH.sub.2).sub.t CH(OZ)CH.sub.3, or Ar;

REFERENCES:
patent: 4874782 (1989-10-01), Bonjouklian et al.
patent: 5242945 (1993-09-01), Caufield et al.
Nomura et al., Chem Pharm Bulletin, 34:5188 (1986).
Kataoka et al., Chemical Abstracts, 84:175144m (1976).
Orno et al., Chemical Abstracts, 81:151976w (1974).

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