Human signal transduction MAPK kinase

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07H 2104

Patent

active

056633149

ABSTRACT:
An isolated nucleic acid molecule which hybridizes under stringent conditions with the nucleic acid shown in SEQ ID NO:32 or its complement or the nucleic acid shown in SEQ ID NO:34 or its complement, and which encodes mitogen activated protein kinase kinase protein.

REFERENCES:
patent: 5405941 (1995-04-01), Johnson
Ray, L. B., and Sturgill, T. W. (1987) Proc. Natl. Acad. Sci. U.S.A. 84, 1502-1506.
Ray, L. B., and Sturgill, T. W. (1988) J. Biol. Chem. 263, 12721-12727.
Ahn, N. G., Weiel, J. E., Chan, C. P., and Krebs, E. G. (1990) J. Biol. Chem. 265, 11487 11494.
Anderson, N. G., Maller, J. L., Tonks, N. K., and Sturgill, T. W. (1990) Nature 343, 651-653.
Boulton, T. G., Yancopoulos, G. D., Gregory, J. S., Slaughter, C., Moomaw, C., Hsu, J., and Cobb, M. H. (1990) Science 249, 64-67.
Sturgill, T. W., and Wu, J. (1991) Biochim. Bioshys. Acta 1092, 350-357.
Cobb, M. H., Boulton, T. G., and Robbins, D. J. (1992) Cell Regul. 2, 965-978.
Thomas, G. (1992) Cell 68, 3-6.
Boulton, T. G., Gregory, J. S., and Cobb, M. H. (1991) Biochemistry 30, 278-286.
Boulton, T. G., Nye, S. H., Robbins, D. J., Y. N., Radziejewska, E., Morgenbesser, S., Depinho, R., Panayotatos, N., Cobb, M.H., and Yancopoulos, G. D. (1991) Cell 65, 663-675.
Pulverer, B. J., Kyriakis, J. M., Avruch, J., Nikolakaki, E., and Woodgett, J.R. (1991) Nature 253, 670-674.
Alvarez, E., Northwood, 1. C., Gonzales, F. A., Latour, D. A., Seth, A., Abate, C., Curran, T., and Davis, R. J. (1991) J. Biol. Chem. 266,15277 15285.
Anderson, N. G., Li, P., Marsden, L. A., Williams, N., Roberts, T. M., and Sturgill, T. W. (1991) Biochem. J. 277, 573-576.
Takishima, K., Griswold-Prenner, I., Ingebritsen, T., and Rosner, M. R. (1991) Proc. Natl. Acad. Sci. U.S.A. 88 2520-2524.
Sturgill, T. W., Ray, L. B., Erickson, E., and Maller, J. L. (1988) Nature 334, 715-718.
Gregory, J. S., Boulton, T. G., Sang, B. C., and Cobb M. H. (1989) J. Biol. Chem. 264, 18397-18441.
Ahn, N. G., and Krebs, E. G. (1990) J. Biol. Chem. 265, 11495 11501.
Payne, D. M., Rossomando, A. J., Martino, P., Erickson, A. K., Her, J.-H., Shabanowitz, J., Hunt, D. F., Weber, M. J., and Sturgill, T. W. (1991) EMBO J. 10, 885 892.
Ahn, N. G., Seger, R., Bratlien, R. L., Diltz, C. D., Tonks N. K., and Krebs, E.G. (1991) J. Biol. Chem. 266, 4220-4227.
Gomez, N., and Cohen, P. (1991) Nature 353, 170-173.
Ahn, N. G., Robbins, D. J., Haycock, J. W., Seger, R., Cobb, M. H., and Krebs, E. G. (1992) J. Neurochem., 59:147-156.
Seger, R., Ahn, N. G., Boulton, T. G., Yancopoulos, G. D., Panayotatos, N Radziejewska, E., Ericsson, L., Bratlein, R. L., Cobb, M. H., and Krebs, E. G. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 6142-6146.
Crews, C. M., Alessandrini, A. A., and Erikson, R. L. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 8845-8849.
Wu, T., Rossomando, A. J., Her, J.-H., Del-Vecchio, R., Weber, M. J., and Sturgill, T. W. (1991) Proc. Natt. Acad. Sci. U.S.A. 88, 9508-9512.
Robbins, D. J., and Cobb, M. H. (1992) Mol. Biol. Cell 3, 299-308.
Tonks, N. K., Charbonneau, H., Diltz, C. D., Fischer, E. H., and Walsh, K. A. (1988) Biochemistry 27, 8695 8701.
Cohen, P., Holmes, C. F. B., and Tsakitani, Y. (1990) Trends Biochem. Sci. 15, 98 102.
Posada, J., and Cooper, J. A. (1992) Science 255, 212-215.
Matsuda, S., Kosako, H., Takenaka, K., Moriyama, K., Sakai, H., Akiyama, T., Gotoh, Y., and Nishida, E. (1992) EMBO J. 11, 973-982.
Seger, R., Ahn, N.G., Posada, J., Munar, E.S. Jenson, A.M. Cooper, J.A., Cobb, M.H. and Krebs, E.G. (1992) J. Biol. Chem. 267, 14373-14381.
Kosako, Gotoh, Y., Matsuda, S., Ishikawa,M. and Nishida,E. (1992) EMBOJ. 11 , 2903-2908.
Shirakabe, K., Gotoh, Y. and Nishida, E. (1992) J. Biol. Chem. 267, 16685-16690.
Nakielny, S., Cohen, P., Wu, J. and Sturgill, T. (1992) EMBO J. 11, 2123-2128.
L'Allemain, G., Her, J.H., Wu, J., Sturgill, T.W. and Weber, M.J. (1992) J. Mol. Cell Biol 12, 2222-2229
Adams P.D. and Parker, P.J. (1 992) Activation of Mitogen-Activated Protein (MAP) Kinase by a MAP Kinase-Kinase J. Biol. Chem. 267, 13135-13138.
Rossomando, A., Wu, J., Weber, M.J. and Sturgill, T.W. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 5221-5225.
Hanks, S.K., Quinn, A.M. and Hunter T. (1988) Science 241, 42-52.
Lee, M.G. and Nurse, P. (1987) Nature 327, 31-33.
Lindberg, R.A., Quinn, A.M. and Hunter, T. (1992) Trends Biochem. Sci. 17, 114-119.
Dent, P., Haser, W., Haystead, T.A.J., Vincent, L.A., Roberts, T.M. and Sturgill, T.W. (I992) Science 257, 1404-1406.
Higgins, D.G. and Sharp, P.M. (1988) Gene 73, 237-246.
Crews, C.M., Alessandrini, A., and Erikson, R.L. (1992; Oct.) Science 258, 478-480.
Crews, C.M., and Erikson, R.L. (1992: Sep.) Proc. Natl. Acad. Sci. USA 89, 8205-8209.
Nakielny, S., Campbell, D.G. and Cohen, P. (1992; Aug.) FEBS 308, 183-189.
Seger, R., Ahn, N.G., Bratlien, R.L., Cobb, M.H. and Krebs, E.G. (1991). Abstract, 15th Intl. Congress of Biochem., Jerusalem, Israel, Aug. 4-8, 1991.
Ahn, N.G., Seger, R.S., Bratlein, R.L., Tonks, N.K., and Krebs, E.G. (1990). Abstract, Fed. Amer. Soc. Exptl. Biol. Med..
Suggs et al., PNAS, 78(1):6613-6617, 1981.
Young et al., PNAS, 80:1194-1198, 1983.
Seger et al. Human T-cell mitogen-activated protein kinase are related to yeast signal transduction kinases. The Journal of Biological Chemistry. vol. 267, No. 36, pp. 25628-25631. Dec. 25, 1992.
Adams et al. Sequence identification of 2,375 human brain genes. Nature. vol. 355, pp. 632-634. Feb. 13, 1992.
Crews et al. The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. Science. vol. 258, pp. 478-480. Oct. 16, 1992.
Molecular cloning: a laboratory manual, 2nd ed. Sambrook et al., eds. Cold Spring Harbor, Cold Spring Harbor Laboratory Press. Chapters 9 and 11 1989.
Teague et al. Nucleotide sequence of the yeast regulatory gene STE7 predicts a protein homologous to protein kinases. Proceedings of the National Academy of Sciences, USA. vol. 83, p. 7371-7375. Oct. 1988.
Ahn et al. Multiple components in an epidermal growth factor-stimulated protein kinase cascade: in vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase. The Journal of Biological Chemistry. vol. 266, No. 7, pp. 4220-4227. Mar. 5, 1991.
Nadin-Davis et al. A gene which encodes a predicted protein kinase can restore functions of the ras gene in fission yeast. The EMBO Journal. vol. 7, No. 4, pp. 985-993. 1988.
Haystead et al. Ordered phosphorylation of p42mapk by MAP kinase kinase. FEBS Letters. vol. 306, No. 1, pp. 17-22. Jun. 1992.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Human signal transduction MAPK kinase does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Human signal transduction MAPK kinase, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human signal transduction MAPK kinase will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-309498

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.