Production of certain imidazopyridinyl-methyl-benzene sulfonamid

Details Production of certain imidazopyridinyl-methyl-benzene sulfonamid Production of certain imidazopyridinyl-methyl-benzene sulfonamid

1992-12-14

1994-01-04

Dentz, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546118, C07D47104

Patent

active

052761533

ABSTRACT:
Compounds of general formula I; ##STR1## wherein: A.sup.1 is .dbd.N--, .dbd.CH-- or .dbd.CR.sup.1 --;
A.sup.2 is .dbd.N--, .dbd.CH-- or .dbd.CR.sup.2 --;
provided that, when one of A.sup.1 and A.sup.2 is a nitrogen atom, the other of A.sup.1 and A.sup.2 is other than a nitrogen atom; wherein the rest of the variables are defined in the specification;
and their pharmaceutically and veterinarily acceptable acid addition salts and hydrates are antagonists of platelet activating factor (PAF) and as such are useful in the treatment or amelioration of various diseases or disorders mediated by PAF.

REFERENCES:
patent: 4804658 (1989-02-01), Manley et al.
patent: 4914108 (1990-04-01), Khanna et al.
patent: 5157026 (1992-10-01), Chakravarty et al.

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