Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1995-06-07
1999-02-23
Spector, Lorraine
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 234, 435 691, 4353201, 435325, 4352523, 43525411, 530350, C12N 1512, C12N 510, C12N 1563
Patent
active
058745629
ABSTRACT:
The present invention relates to a member of a novel gene family referred to as developmentally-regulated endothelial cell locus-1 (del-1). In particular, the invention relates to del-1 nucleotide sequence, Del-1 amino acid sequence, methods of expressing a functional gene product, and methods of using the gene product.
REFERENCES:
patent: 4868112 (1989-09-01), Toole, Jr. et al.
patent: 5096825 (1992-03-01), Barr et al.
patent: 5270170 (1993-12-01), Schatz et al.
patent: 5505955 (1996-04-01), Peterson et al.
patent: 5506107 (1996-04-01), Cunningham et al.
patent: 5508199 (1996-04-01), Gonzalez et al.
Anderson, 1990, "Adhesion molecules and animal development," Experientia 46:2-13.
Brooks et al., 1994, "Integrin .alpha..sub.v .beta..sub.3 Antagonists Promote Tumor Regression by Inducing Apoptosis of Angiogenic Blood Vessels," Cell 79:1157-1164.
Couso and Arias, 1994, "Notch is Required for wingless Signaling in the Epidermis of Drosophila," Cell 79:259-272.
Crowley et al., 1985, "Phenocopy of Discoidin I-Minus Mutants by Antisense Transformation in Dictyostelium," Cell 43:633-641.
Fortini and Artavanis-Tsakonas, 1994, "The Suppressor of Hairless Protein Participates in Notch Receptor Signaling," Cell 79:273-282.
Fukuzawa and Ochiai, 1988, "Monoclonal Antibodies against Discoidin I and Discoidin II of the Cellular Slime Mold, Dictyostelium discoideum," J. Biochem 103:884-888.
Henderon et al., 1994, "lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans," Development 120:2913-2924.
Hynes, 1992, "Integrins: Verstility, Modulation, and Signaling in Cell Adhesion," Cell 69:11-25.
Johnson et al., 1993, "A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain," Proc. Natl. Acad. Sci. U.S.A. 90:5677-5681.
Kane and Davie, 1986, "Cloning of a cDNA coding for human factor V, a blood coagulation factor homologous to factor VIII and ceruloplasmin," Proc. Natl. Acad. Sci. U.S.A. 83:6800-6804.
Kronmiller et al., 1991, "EGF Antisense Oligodeoxynucleotides Block Murine Odontogenesis in Vitro," Dev. Biol. 147:485-488.
Larocca et al., 1991, "A M.sub.r 46,000 Human Milk Fat Globule Protein That Is Highly Expressed in Human Breast Tumors Contains Factor VIII-like Domains," Cancer Res. 51:4994-4998.
Main et al, 1992, "The Three-Dimensional Structure of the Tenth Type III Module of Fibronectin: An Insight into RGD-Mediated Interactions," Cell 71:671-678.
Orsini et al., 1991, "Radioimmunoassay of Epidermal Growth Factor in Human Saliva and Gastric Juice," Clinical Biochem. 24:135-141.
Rebay et al., 1991, "Specifc EGF Repeats of Notch Mediate Interactions with Delta and Serrate: Implications for Notch as a Multifunctional Receptor," Cell 67:687-699.
Stubbs et al., 1990, "cDNA cloning of a mouse mammary epithelial cell surface protein reveals the existence of epidermal growth factor-like domains linked to factor VIII-like sequences," Proc. Natl. Acad. Sci. U.S.A. 87:8417-8421.
Hillier et al., GenBank Accession Number R56339 (accessed Dec. 18, 1997), May 23, 1995.
Reddy et al., GenBank Accession Number T09857 (accessed Dec. 18, 1997), Nov. 29, 1993.
Familari et al., GenBank Accession Number L14608 (accessed Dec. 18, 1997), Jul. 14, 1993.
Dumont et al., The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors, Oncogene 8(5):1293-1301, May 1993.
Hogan Bridgid
Quertermous Thomas
Snodgrass H. Ralph
Zupancic Thomas Joel
Kaufman Claire M.
Progenitor, Inc.
Spector Lorraine
Vanderbilt University
LandOfFree
Nucleic acid encoding developmentally-regulated endothelial cell does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nucleic acid encoding developmentally-regulated endothelial cell, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid encoding developmentally-regulated endothelial cell will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-308334