Phosphonoalkylquinolin-2-ones as novel antagonists of non-NMDA i

Details Phosphonoalkylquinolin-2-ones as novel antagonists of non-NMDA i Phosphonoalkylquinolin-2-ones as novel antagonists of non-NMDA i

1992-12-02

1994-08-30

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21514, C07D21518, C07D215227, A61K 31675

Patent

active

053429460

ABSTRACT:
The present invention pertains to antagonists of excitatory amino acid receptors, their method of preparation as well as compositions pertaining to them, which have the general formula: ##STR1## wherein n is 0, 1, 2, or 3; R.sub.1 and R.sub.2 are selected from the group consisting of hydrogen, halogen, halomethyl, nitro, amino, alkoxy, hydroxyl, hydroxymethyl, C.sub.1 to C.sub.6 lower alkyl and C.sub.7 to C.sub.12 higher alkyl, aryl and aralkyl; and the pharmaceutically acceptable salts thereof.

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