Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1995-06-01
1997-09-02
Arthur, Lisa B.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 6, 435 71, 435 912, 435 2, 210789, 210782, 424 9372, 424 9374, C12Q 170, C12Q 168, B01D 3315, B01D 2126
Patent
active
056630450
ABSTRACT:
The present invention provides a method for testing a blood unit for viral contamination without rendering the blood unit unusable for therapeutic applications. The method comprises the steps of: removing and collecting from a blood unit a majority of the leukocytes present therein; and using the collected leukocytes to test the blood unit for viral contamination. The present invention also provides a method for validating viral inactivation processes.
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Perrow, The Preparation of Leucocyte Homogenates for Enzymatic Assays, New Zealand Journal of Laboratory Techniques, vol. 31, No. 1, pp. 6-9 (1977).
Bruisten et al, Efficiency of White Cell Filtration and a Freeze-Thaw Procedure for Removal of HIV-infected Cells from Blood, Transfusions, vol. 30, No. 9, pp. 833-837 (1990).
Arthur Lisa B.
Barrett Robert M.
Baxter International Inc.
Price Bradford R. L.
Serewicz Denise M.
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