Phosphorus-containing HMG-COA reductase inhibitors, new intermed

Details Phosphorus-containing HMG-COA reductase inhibitors, new intermed Phosphorus-containing HMG-COA reductase inhibitors, new intermed

1991-12-19

1994-01-04

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

558197, 558198, 560183, C07F 902, C07C 6973, A61K 3166

Patent

active

052760219

ABSTRACT:
Compounds which are useful as inhibitors of cholesterol biosynthesis and thus as hypocholesterolemic agents are provided which have the structure ##STR1## wherein R is OH, or salts thereof or lower alkoxy;

REFERENCES:
patent: 4613610 (1986-09-01), Wareing
patent: 4647576 (1987-03-01), Hoefle
Tetrahedron Letter, vol. 29, No. 8, 929-930, 1988, Synthesis of a novel HMG-COA reductase inhibitor.

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