Cedar pollen protein and use thereof in treating, preventing, an

Details Cedar pollen protein and use thereof in treating, preventing, an Cedar pollen protein and use thereof in treating, preventing, an

1996-12-24

1999-02-23

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

424 981, 4241851, 4242761, 530379, 530395, A61K 3816, A61K 3936, A61K 4900, C07K 14415

Patent

active

058744010

ABSTRACT:
A protein having a molecular weight of 44,000-54,000 daltons, isoelectric point of 8.5-9.2 and specific sugar chain is prepared from a cedar pollen. The protein induces pollenosis and can be suitably used as desensitization agent because it induces immunoglobulin antibody which is effective for desensitization, but does not substantially induce immunoglobulin E antibody, a major factor causative of side effects including anaphylaxis shock. Therefore, the protein can be advantageously used in the treatment, prevention and/or diagnosis of pollenosis.

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