Method for dissolving collagen-containing skin tissues

Details Method for dissolving collagen-containing skin tissues Method for dissolving collagen-containing skin tissues

1977-09-19

1980-07-01

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435839, 435836, 435834, 435832, 435913, C12P 2106

Patent

active

042107210

ABSTRACT:
A method for dissolving collagen-containing skin tissue by hydrolyzing said tissue in a first stage in the presence of urea with an alkaline proteinase having an activity optimum between pH 9 and 13, said hydrolysis proceeding in a hydrolysis medium which is initially in the pH region optimum for the enzyme employed, and optionally further hydrolyzing said tissue in at least one further stage by adding a weakly alkaline, neutral, or acid proteinase to said hydrolysis medium.

REFERENCES:
patent: 3034852 (1962-05-01), Nishihara
patent: 3530037 (1970-09-01), Nishihara
patent: 3939040 (1976-02-01), Monsheimer et al.
patent: 4019956 (1977-04-01), Saby

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