Blood compatible polymers and applications thereof

Details Blood compatible polymers and applications thereof Blood compatible polymers and applications thereof

1977-02-07

1980-07-01

Spear, Jr., Frank A.

Liquid purification or separation

With alarm, indicator, register, recorder, signal or...

Responsive to fluid flow

55 16, 55158, 210321B, 422 48, B01D 1300, A61M 103

Patent

active

042105293

ABSTRACT:
Fluoroacylation of ethyl cellulose has been found to result in good gas permeability and blood compatibility for polymeric layers made from the resulting fluorinated esters. The fluoroacylated ethyl cellulose has good hydrolytic stability at blood pH and under sterilization conditions (e.g. 100.degree. C.). For use in blood oxygenation devices, implantable biomedical devices, blood sampling of analysis or purification devices, etc., it is preferred that the fluoroacylated ethyl cellulose be substantially free of residual OH and have a fluorine content above 10% by weight (e.g. at least about 12% by weight).

REFERENCES:
patent: 3122479 (1964-02-01), Smith
patent: 3342729 (1967-09-01), Strand
patent: 3551244 (1970-12-01), Forrester et al.
patent: 4008047 (1977-02-01), Petersen
Petersen, R. J., et al., "Provide Ultrathin Membranes for Evaluation in Blood Oxygenators", Report No. NIH-NHLI-71-2364D-1, Aug., 1972, pp. 111, 1, 2, 8-10, 13, 18-22, 26 & 27.

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