Protease inhibitors

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2604045, C07C10346

Patent

active

045512795

ABSTRACT:
This invention relates to methods of preventing or reducing the degradation of elastin and other proteins and thereby preventing or retarding the disease states caused by said degradation by administering compounds, some of which are novel, of the formula: ##STR1## or their pharmacologically acceptable salts.

REFERENCES:
Nicolau et al., "N-Acylsarcosines as Inhibitors of Respiration and Glycolysis and Glycolytic Enzymes", Biochemistry and Biophysics, vol. 129, 1969, pp. 357-361.
Parker et al., "5-(Tetradecyloxy)-2-Furancarboxylic Acid and Related Hypolipidemic Fatty Acid-Like Alkyloxyarylcarboxylic Acids", Journal of Medicinal Chemistry, vol. 20, 1977, pp. 781-791.

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