Method for producing polypeptide via bacterial fermentation

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 712, 530401, C12D 2100

Patent

active

053427637

ABSTRACT:
A process for producing a polypeptide of interest from fermentation of bacterial host cells comprising nucleic acid encoding the polypeptide is provided. In this method, the host cells employed have an inactivated electron transport chain. Further provided is a method for determining if a particular bacterial cell culture has a propensity for dissolved oxygen instability when fermented on a large scale.

REFERENCES:
patent: 4476224 (1984-10-01), Adler
patent: 4762784 (1988-08-01), Keith et al.
patent: 5049493 (1991-09-01), Khosla et al.
patent: 5182195 (1993-01-01), Nakahama et al.
Yegneswaran, P. K., et al., Biotechnology and Bioengineering, vol. 38, pp. 1203-1209, Dec. 5, 1991.
Wu, G., et al., Journal of General Microbiology, vol. 138, pp. 2101-2112, Oct. 1992.
Hopkins, D. J., et al., Biotechnology and Bioengineering, vol. 29, pp. 85-91, Jan. 1987.
Li, X., et al., Journal of Industrial Microbiology, vol. 9, pp. 1-10, Jan. 1992.
Guideline on General Principles of Process Validation, May 1987, prepared by the Center of Drugs and Biologics and Center for Devices and Radiological Health, FDA, Maintained by Div. of Manufacturing and Product Quality (Div. HFN-320), Office of Compliance, Center for Drugs and Biologics, FDA, Rockville, Md. 20857.
Poole, Biochimica et Biophysica Acta, 726:205-243 (1983), "Bacterial Cytochrome Oxidases".
Edwards et al., FEBS Letts., 128(2):205-207 (1981), "Photochemical Action Spectra of Bacterial a-And O-Type Oxidaess Using a Dye Laser".
Poole et al. in Microbial Gas Metabolism: Mechanistic, Metabolic and Biotechnological Aspects, Poole et al., eds., Society for General Microbiology by Academic Press, pp. 31-62 (1985).
Castor et al., J. Biol. Chem., 234:1587-1592 (1959), "Photochemical Determinations of the Oxidases of Bacteria".
Kranz et al., J. Bacteriol., 161(2):709-713 (1985), "Immunological Investigation of the Distribution of Cytochromes Related to the Two Terminal Oxidases of E. coli in Other Gram-Negative Bacteria".
Laszlo et al., J. Bacteriol., 159(2):663-667 (1984), "Cytochrome o as a terminal Oxidase and Receptor for Aerotaxis in Salmonella typhimurium".
Brock et al., Biology of Microorganisms, Prentice Hall, New Jersey, p. 673.
Doelle et al., "Transitional Steady-State Investigation during Aerobic-Anaerobic Transition of Glucose Utilization by Escherichia coli K-12" Eur. J. Biochem. 83:479-484 (1978).
Harrison et al., "The Effect of Growth Conditions on Respiratory Activity and Growth Efficiency in Facultative Anerobes Grown in Chemostat Culture" J. of General Microbiology 68:35-43 (1971).
Degin et al., "Theory of Oscillations of Respiration Rate in Continuous Culture of Klebseiella aerogenes" J. Theoret. Biol. 22:238-248 (1969).
Harrison et al. "The Influence of Dissolved Oxygen Concentration on the Respiration and Glucose Metabolism of Klebsiella aerogenes during Growth" J. Gen. Microb. 48:193-211 (1967).
Fu & Lin, Mol. Gen. Genet., 226: 209-213 (1991).
Anrako & Gennis, TIBS, 12: 262-266 (Jul. 1987).
Poole & Ingledew in Escherich a coli and Salmonella Typhimurium: Cellular & Molecular Biology, Neidbardt et al., eds., American Society for Microbiology, Washington, D.C., 1987, pp. 170-200.
Wallace & Young, Biochimica et Biophyisica Acta, 461: 84-100 (1977).
Oden et al., Gene, 96: 29-36 (1990).
Oden & Gennis, J. Bacteriol., 173(19): 6174-6183 (1991).
Kelly et al., J. Bacteriol., 172(10): 6010-6019 (1990).
Juchi et al., J. Bacteriol., 172(10): 6020-6025 (1990).
Soberon et al., J. Bacteriol., 172(3): 1676-1680 (1990).
Poole et al., J. Gen. Microbiol., 135: 1865-1874 (1989).
Fang et al., J. Biol. Chem., 264(14): 8026-8032 (1989).
James et al., FEMS Microbiol. Letters, 58:277-282 (1989).
Green et al., J. Biol. Chem., 263(26):13138-13143 (1988).
Soberon et al., J. Bacteriol., 171(1): 465-472 (1989).
Sharma et al., Indian J. Microbiol., 27(1-4)26-31 (1987).
Yang, Arch. Microbiol., 144:228-232 (1986).
Matsushita & Kaback, Biochem., 25:2321-2327 (1986).
Tamura-Lis & Webster, Archives Biochem. & Biophys., 244(1): 285-291 (1986).
Au et al., J. Bacteriol., 161(1):123-127 (1985).
McInerney et al., FEBS, 141:447-452 (1984).
Lorence et al., J. Bacteriol, 157(1):115-121 (1984).
Kranz et al., J. Bacteriol., 156(1):115-121 (1983).
Green & Gennis, J. Bacteriol., 154(3):1269-1275 1275 (1983).
Bryan & Kwan, Antimacrob. Agents & Chemother, 19(6):958-964 (1981).
Willison et al., FEMS Microbiol Lets., 10:249-255 (1981).
Willison & Haddock, FEMS Microbiol. Lets., 10:53-57 (1981).
Hoffman et al., Eur. J. Biochem., 105:177-185 (1980).
Hoffman et al., Eur. J. Biochem., 100:19-27 (1979).
Haddock & Schairer, Eur. J. Biochem., 35:34-45 (1973).
Habina et al., EMBO J., 8(12):3571-3579 (1989).
Dikshit et al., Arch. Biochem. & Biophys., 293(2):241-245 (1992).
Lemieux et al., J. Biol. Chem., 267(3):2105-2113 (1992).
Minagawa et al., J. Biol. Chem., 267(3):2096-2104 (1992).
Dassa et al., Mol. Geo. Genet., 229:341-352 (1991).
Williams et al., Biochem. J., 276:555-557 (1991).
Poustinen et al., Biochem., 30:3936-3942 (1991).
Denis et al., J. Biol. Chem., 265(30):18095-18097 (1990).
Chepuri et al., Biochim. Biophys. Acta, 1018:124-127 (1990).
Andersson & Roth, J. Bacteriol., 171(12):6734-6739 (1989).
Poustinen et al., FEBS, 249(2):163-167 (1989).
Daldal, J. Bacteriol., 170(5):2388-2391 (1988).
Poole & Williams, FEBS, 231(1):243-246 (1988).
Georgiou et al., J. Bacteriol., 169(5):2107-2112 (1987).
O'Brian & Maier, J. Bacteriol., 161(2):507-514 (1985).
Green et al., J. Biol. Chem., 259(12):7994-7997 (1984).
Au et al., J. Bacteriol., 157(1):122-125 (1984).
Matsushita et al., PNAS USA, 80:4889-4893 (1983).
Sasarman, Rev. Can. Biol., 31:317-319 (1972).
Van der Oost et al., EMBO J., 11(9):3209-3217 (1992).
Deutch, 92nd Gen. Mtg. of the Am. Soc. for Microbiology, May 26, 26-30, 1992, p. 272, abstract No. K-97.
Mogi et al., Biophys. J., 61:A284, abstr. #1631 (1992).
Tron & Lemesle-Meunier, Curr. Genet., 18:413-419 (1990).
Shioi et al., J. Bacteriol., 170(12):5507-5511 (1988).
Oden & Gennis, J. Gen. Biol., 107:624a, Abstr. #3540 (1988).
Webster & Georgiou, Fed. Proc., 44:678, Abstr. #1564 (1985).
Terriere et al., BBRC, 111(3):830-839 (1983).
Green & Gennis, Fed. Proc., 41:894, Abstr. #3652 (1982).
Tamura-Lis & Webster, Fed. Proc., 41: 749, abstr. #2799 (1982).
Green et al., Fed. Proc., 40:1669, Abstr. #749 (1981).
Willison & John, J. Gen. Microbiol., 115:443-450 (1979).
Hashimoto & Hino, J. Sci. of Hiroshima Univ., Series B, Div. 2, 15:103-113 (1975).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for producing polypeptide via bacterial fermentation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for producing polypeptide via bacterial fermentation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for producing polypeptide via bacterial fermentation will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-29457

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.