Method for producing polypeptide via bacterial fermentation

Details Method for producing polypeptide via bacterial fermentation Method for producing polypeptide via bacterial fermentation

1992-11-23

1994-08-30

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 712, 530401, C12D 2100

Patent

active

053427637

ABSTRACT:
A process for producing a polypeptide of interest from fermentation of bacterial host cells comprising nucleic acid encoding the polypeptide is provided. In this method, the host cells employed have an inactivated electron transport chain. Further provided is a method for determining if a particular bacterial cell culture has a propensity for dissolved oxygen instability when fermented on a large scale.

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