Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1986-09-23
1991-02-26
Moskowitz, Margaret
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530350, 530359, 530315, 530402, 530403, 530406, 530427, 530806, 4352402, 4352401, 435820, 424 88, 514 8, 514 2, A61K 3939, A61K 4100, A61K 4505
Patent
active
049961942
ABSTRACT:
Composition for the prevention and treatment of autoimmune diseases are provided which comprise as an active ingredient membrane material shed from autoimmune T lymphocytes, or activated T lymphocytes which are treated by a pressure application and releases process. There is also provided processes for obtaining such active materials and for preparing pharmaceutical compositions containing them.
REFERENCES:
patent: 4046877 (1987-09-01), White et al.
patent: 4133804 (1979-01-01), Bach et al.
patent: 4634590 (1987-01-01), Cohen et al.
patent: 4690915 (1987-09-01), Rosenberg
Forman, J. Immunol., 118(5):1755-, (1977).
Thomas, J. Immunol., 121(5):1760-, (1978).
Dabrowska et al, Chem Abs, 98: 175125v, (1983).
Gallaher et al, Chem. Abs., 105: 224314e (1986).
Maron et al, J. Immunol., 131(5) (1983), pp. 2316-2321.
Holoshitz et al, J. Immunol., 131(6), 2810-, (1983).
Holoshitz et al, Science, 219, 56-58 (1983).
Lider et al, PNAS (USA), 84, 4577-4580 (Jul. 1987).
Lider et al, Ann. N.Y. Acad. Sci., 475, pp. 267-273 (Jul. 1986).
Sridama et al, J. Clin. End. Met., 54(2), 316 (1982).
Iwatani et al, J. Clin. End. Met., 56(2), 251 (1983).
Ben-Nun et al, "The Rapid Isolation of Clonable Antigen-Specific T Lymphocyte Lines Capable of Mediating Autoimmune Encephalomyelitis", Eur. J. Immunol., 11:195-199 (1981).
Ben-Nun et al, "Spontaneous Remission and Acquired Resistance to Autoimmune Encephalomyelitis (EAE) are Associated with Suppression of T Cell Reactivity: Suppressed EAE Effector T Cells Recovered as T Cell Lines", J. Immunol., 128:1450-1457 (1982).
Ben-Nun et al, "Experimental Autoimmune Encephalomyelitis (EAE), Mediated by T Cell Lines: Process of Selection of Lines and Characterization of the Cells", J. Immunol., 129:303-308 (1982).
Ben-Nun et al, "Experimental Autoimmune Eucephalomelitis (EAE) in Genetically Resistant Rats: PVG Rats Resist Active Induction of EAE but are Susceptible to and Can Generate EAE Effector T Cell Lines", J. Immunol, 129:918-919 (1982).
Ben-Nun et al, "Vaccination Against Autoimmune Encephalomyelitis with T-Lymphocyte Line Cells Reactive Against Myelin Basic Protein", Nature, 292:60-61 (1981).
Ben-Nun et al, "Vaccination Against Autoimmune Encephalomyelitis (EAE): Attenuated Autoimmune T Lymphocytes Confer Resistance to Induction of Active EAE but not to EAE Mediated by the Intact T Lymphocyte Line", Eur. J. Immunol, 11:949-952 (1981).
Muller et al, "Passive Shedding of Erythrocyte Antigens Induced by Membrane Rigidification", Exp. Cell Research, 136:53-62 (1981).
Choug, "Pressure Effects on Liposomes, Biological Membranes and Membrane-Bound Proteins", Diss. Abstr. Int. B, 43 (9), 2876 (1983).
Zimmerman et al, "The Effects of Hydrostatic Pressure on Cell Membranes", Chemical Abstracts, 88:17431f (1978).
MacDonald, "Molecular and Cellular Effects of Hydrostatic Pressure; A Physiologist's View", Chemical Abstracts, 95:110223u (1981).
Borochor et al, "Vertical Displacement of Membrane Proteins Mediated by Changes in Microviscosity", Chemical Abstracts, 86:53224h (1977).
Shinitzky et al, "Regulation of Tumor Growth by Lipids, Possible Clinical Applications", Chemical Abstracts, 98:137302t (1983).
Clark et al, "X-Ray Diffraction Studies of Globular Proteins III, The Action of Formaldehyde on Proteins", Chemical Abstracts, 31:3071-3072 (1937).
Fagraeus et al, "The Effect of Colchicine on Circulating Antibodies Antibody-Producing Tissues, and Blood Cells in Rats", Chemical Abstracts, 48:3535g (1954).
Jung et al, "Linkage of Formaldehyde to and its Effect on Erythrocytes", Chemical Abstracts, 49:6338f (1955).
Schroeder, "Contractile Ring, I. Fine Structure of Dividing Mammalian (Mela) Cells and the Effect of Cytochalasin B", Chem Abst., 75:61744r (1971).
Carter, "Cytochalasins as research tools in cytology", Chem. Abs, 77:29524z (1972).
Shinitzky et al, "Microviscosity Parameters and Protein Mobility in Biological Membranes", Chem. Abs., 84:160894g (1976).
Cohen, "Regulation of Autoimmune Disease Physiological and Therapeutic", Immunological Review, 94, 5-22 (1986).
Lider et al, "Anti-Idiotypic Network Induced by T Cell Vaccination Against Experimental Antimmune Encephalomyelitis", Science, 239, 181-183, Jan. 8, 1988.
Cohen Irun R.
Shinitzky Meir
Kushan Jeff
Moskowitz Margaret
Yeda Research and Development Co. Ltd.
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