Pharmacological use of uridine in the treatment of nervous disor

Details Pharmacological use of uridine in the treatment of nervous disor Pharmacological use of uridine in the treatment of nervous disor

1989-06-19

1990-10-02

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

A61K 3170

Patent

active

049607596

ABSTRACT:
Disorders due to an altered balance of dopamine release by the cerebral dopaminergic system, such as schizophrenia and Parkinson's disease, can be treated by administration of uridine which is a specific agent for the protection of the cholecystokinin level in the brain tissue.

REFERENCES:
Hokfelt et al., Evidence for Coexistence of Dopamine and CCK in Mesa-Limbic Neurones., Nature, 285, 476-478 (June 1980).
Herbert Y. Meltzer, M. D., Psychopharmacology, Raven Press, 1987, pp. 721-722, 736-737, 1137-1138 and 1258-1260.
Robert George et al., Annual Review of Pharmacology and Toxicology, 23, 7-9, 116. (May 1983).
Chem. Abst., 104-122947a, (1986).

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