Column-packing material for gel-permation chromatography, method

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Processes of preparing a desired or intentional composition...

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523218, 521 54, 521134, 521139, 521140, 524577, 524578, 210635, C08J 940, C08J 942

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active

054280672

ABSTRACT:
A column packing material to be used in gel permeation chromatography (GPC) consists of support particles with a mean particle diameter of 1 to 50.mu. of which the matrix is formed by an inorganic or organic, polymeric and porous hard material with a mean pore diameter of 6 to 50 nm and a pore volume of 0.1 to 3 ml/g, the matrix pores containing chemically bound polymer chains. The column packing material of the invention is characterized in that the polymer chains consist of linear, permeable and not-crosslinked polymers with an upper exclusion limit between 200 and 200,000, the pores of the matrix being entirely filled by the polymer chains. The method of the invention is characterized in that the pores of the support particles are filled by polymer chains chemically bound to the pore surfaces, these polymer chains being permeable to solvents and partly to dissolved substances.

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Kremmer, Tibor, in Gel Chromatography, 1979, pp. 67-68.
Brock, Thomas, Membrane Filtration, 1983, pp. 290-291.
Monrabal, B. Chromatogr. Sci. 19, 1981, pp. 79-98.
Engelhardt et al, High Performance Exclusion Chromatorgraphy of Water-Soluble Polymers with Chemically Bonded Stationary Phases, Journal of Chromatography, 1979, pp. 308-319.

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