Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-10-10
1995-06-27
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142352, 514255, 514311, 514313, 514314, 544 62, 544128, 544363, 546176, A61K 3154, C07D21514
Patent
active
054280338
ABSTRACT:
Compounds having the formula I: ##STR1## are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.
REFERENCES:
patent: 4833161 (1989-05-01), Wolff et al.
patent: 4851409 (1989-07-01), Young et al.
patent: 5104882 (1992-04-01), Young et al.
Belley Michel L.
Labelle Marc
Leger Serge
Roy Patrick
Xiang Yi B.
Covington Raymond
Ivy C. Warren
Merck Frosst Canada Inc.
Rose David L.
Yang Mollie M.
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