Human D5 dopamine recepltor gene and uses

Details Human D5 dopamine recepltor gene and uses Human D5 dopamine recepltor gene and uses

1991-11-13

1995-06-27

Draper, Garnette D.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 691, 4353201, 536 235, 536 2431, C12N 1512

Patent

active

054279429

ABSTRACT:
The present invention relates to the isolation, characterization and pharmacological uses for the human D5 dopamine receptor, the gene corresponding to this receptor, pseudogenes of this receptor gene, a recombinant eukaryotic expression vector capable of expressing the human D5 dopamine receptor in cultures of transformed eukaryotic cells and such cultures of transformed eukaryotic cells that synthesize the human D5 dopamine receptor. The invention relates to the biochemical and physiological characterization of the human D5 dopamine receptor and the development and testing of drugs useful for treating or preventing human disease.

REFERENCES:
patent: 5215915 (1993-06-01), Tiberi et al.
Nature: 347:76-79, Sep. 6, 1990, Zhou et al. Cloning and Expression of Human and Rat D, Dopamine Receptor.
P.N.A.S. 88: 9174-9179, Oct. 1991, Grandy et al. Multiple Human D5 Dopamine Receptor Genes: A functional Receptor and two Pseudo Genes.
P.N.A.S. 88: 7491-7495, Sep. 1991, Tiberi et al. Cloning, Molecular Characterization, and Chromasome Assignment of a Gene Encoding a Second D.sub.1 . . . .
Nature 347:72-76, 6 Sep. 1990, Dearry, et al. Molecular Cloning and Expression of the Gene for a human D.sub.1 Dopamine Receptor.
Nucl. Acad. Res. 13: 4739-4749, 1985, Hauptmann et al.
Cooper et al., The Biochemical Basis of Neuropharmacology, 3rd ed. 1978 Oxford University Press: New York, pp. 161-195.
Kebabian and Calne, Nature 277: 93-96 (1979).
Senogles et al., Biochemistry 25: 749-753 (1986).
Sengoles et al., J. Biol. Chem. 263: 18996-19002 (1988).
Gingrich et al., Biochemistry 27: 3907-3912 (1988).
Amlaiky et al., Mol. Pharmacol. 31: 129-134 (1987).
Niznik et al., Biochemistry 27: 7594-7599 (1988).
Amlaiky and Caron, J. Biol. Chem. 260: 1983-1986 (1985).
Amlaiky and Caron, J. Neurochem. 47: 196-204 (1986).
Jarvie et al., Mol. Pharmacol. 34: 91-97 (1988).
Sokoloff et al., Nature 347: 146-151 (1990).
Seeman et al., Neuropsychopharm. 1: 5-15 (1987).
Seeman, Synapse 1: 133-152 (1987).
Bunzow et al., Nature 336: 783-787 (1988).
Grandy et al., Proc. Natl. Acad. Sci. U.S.A. 86: 9762-9766 (1989).
Dal Toso et al., EMBO J. 8: 4025-4034 (1989).
Zhou et al., Nature 347: 76-80 (1990).
Sunahara et al., Nature 347: 80-83 (1990).
Van Tol et al., Nature 350: 610-614 (1991).
Sunahara et al., Nature 350: 615-619 (1991).

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