Octahydro-1H-benzo[4,5]furo[3,2-e]-isoquinoline analgesic and na

Details Octahydro-1H-benzo[4,5]furo[3,2-e]-isoquinoline analgesic and na Octahydro-1H-benzo[4,5]furo[3,2-e]-isoquinoline analgesic and na

1979-07-09

1981-01-06

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546 66, A61K 3147, C07D21704

Patent

active

042436680

ABSTRACT:
Octahydro-1H-benzo[4,5]furo[3,2-e]isoquinoline compounds and processes for their manufacture are provided. The compounds correspond to the formula ##STR1## These compounds exhibit both analgesic and narcotic antagonistic properties, as well as low abuse liability.
Novel intermediate compounds are also provided which have the formula ##STR2##

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A. Schultz et al., J.A.C.S., 100: 7, 2150-2162, Heteroatom Directed Photoarylation, Synthetic Potential of the Heteroatom Oxygen.

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