Process for separating material from mixture using displacement

Details Process for separating material from mixture using displacement Process for separating material from mixture using displacement

1994-04-05

1995-06-27

Therkorn, Ernest G.

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

210656, 210659, 2101982, B01D 1508

Patent

active

054276861

ABSTRACT:
A separation process is described for separating a known material from a mixture of materials (which may contain unknown materials) using displacement chromatography. The process comprises passing a mixture of materials, including a known material to be recovered, dissolved in a liquid carrier, if necessary, through a first packed column and into a second packed column until all of the known material has passed through the first column and has been loaded onto the stationary phase packing in the second column. A displacement agent, capable of being more strongly bound on the stationary phase packing in the second column than the known material, is then passed through the second column to displace from that column all of the materials in the mixture less strongly bound than the known material, and then to displace the known material from the second column. The columns are then regenerated, preferably by passing a carrier directly through column 2 (in the forward direction of flow) and then passing the effluent from column 2 through column 1 in a reverse direction. The flow through column 2 is continued until all of the displacement agent has been removed from column 2. In one embodiment, a solvent is also counter flushed through the first column to dissolve any precipitates therein.

REFERENCES:
patent: 3920398 (1975-11-01), Small
patent: 3925019 (1975-12-01), Small
patent: 3971842 (1976-07-01), Ewbank
patent: 4394353 (1983-07-01), Miyake
patent: 4599175 (1986-07-01), Yamamizu
patent: 4600566 (1986-07-01), Fujine
patent: 4915843 (1990-04-01), Taniguchi et al.
patent: 5028696 (1991-07-01), Torres
Cramer, Steven M., et al., "Recent Advances in the Theory and Practice of Displacement Chromatography," Separation and Purification Methods, vol. 19, No. 1, 1990, pp. 31-91.
Horvath, Csaba, "Displacement Chromatography: Yesterday, Today and Tomorrow," in The Science of Chromatography, edited by Fabrizio Bruner, Amsterdam: Elsevier, 1985, pp. 179-203.

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