Ventilation controlled rate responsive cardiac pacemaker

Surgery – Truss – Pad

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128734, 128723, A61N 100

Patent

active

049191365

ABSTRACT:
The rate of pacing pulses in a rate responsive pacemaker is controlled from data representing respiration characteristics in a patient detected by intracardiac impedance measurements for more reliable control. These measurements give more reliable data for the critical pacing pulse rate control then prior art impedance measurements within the human thorax, which necessarily detect impedance changes in various tissues following respiration activity. Thus the respiration produces opposite effects on variations of impedance of pulmonary tissue and of blood, which partially cancel each other and therefore compromise the validity of transthoracic impedance based measurements of respiration. Improved respiratory activity signals reducing the unwanted effects of the pulmonary impedance changes are obtained by measuring impedance strictly within the heart. The intracardiac impedance measurements are filtered through a low pass filter to isolate the ventilation activity where amplitude is related to the tidal volume. Nonlinearities of this amplitude signal related to the physioloical activity of a patient are found to be related inversely to the respiratory rate, and are accordingly corrected to provide control signals faithfully representing the true ventilatory tidal volume. Thus, ventilation signals representing tidal volume become a reliable factor for use in pacing pulse rate control.

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"Comparative Evaluation of Two Respiratory Sensing Rate Responsive Pace-Makers," Chu-Pak Lau, et al., PACE, vol. 11, Apr. '88, p. 487.

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