Chemical methods

Details Chemical methods Chemical methods

2008-07-29

2008-07-29

Aulakh, Charanjit S (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S045000, C546S046000, C546S039000

Reexamination Certificate

active

07405301

ABSTRACT:
This invention relates to a method for N-demethylating an N-methyl morphinane comprising the steps of: (i) treating said N-methyl morphinane with an oxidizing agent to form the N-oxide morphinane; and (ii) treating said N-oxide morphinane with a reducing agent. This invention also relates to a method for oxidizing a Δ7-morphinane compound to a Δ6, Δ8-morphinane compound, comprising the steps of treating said Δ7-morphinane with γ-MnO2for a time and under conditions sufficient to oxidize said Δ7-morphinane, and treating the γ-MnO2with glycol or a derivative thereof, and/or an inorganic salt.

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