Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector
Reexamination Certificate
2008-03-18
2008-03-18
Ewoldt, G. R. (Department: 1644)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
C424S198100
Reexamination Certificate
active
07344717
ABSTRACT:
A novel use of the known protein Erythropoietin (EPO) and/or a derivative and/or a fragment thereof is disclosed. EPO is used as a pharmaceutical for the treatment of chronic inflammations. A particularly beneficial result is seen in patients suffering from rheumatoid arthritis (RA). Significant effects are seen in clinical variables such as morning stiffness, swollen joints, and the like.
REFERENCES:
patent: 0 269 394 (1988-06-01), None
patent: 2 171 304 (1986-08-01), None
patent: 2171304 (1986-08-01), None
Robbins Pathological Basis of Disease, 4th edition, pp. 190-193, 1989.
Smilek, D et al., PNAS 88:9633-37, A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce EAE, Nov. 1991.
Toshihide, S et al. Kyushu Riumachi (Kyushu Journal of Rheumatology, 1991, 10(1):19-23. English Abstract Only.
Petterson, T et al. Scandinavian Journal of Rheumatology, 1993, 22 (4):188-193.
Swaak et al. Clin. Exp. Rheumatol, p. 577, 1994.
Chemical Abstracts, vol. 101, No. 3, Jul. 16, 1994, Biemond et al., “Iron Mobilization From Ferritin by Superoxide Derived From Stimulated Polymorphonuclear . . . ”.
Annals of Hematology, vo. 65, No. 6, Dec. 1992, pp. 265-268, G. Vreugdenhil et al, “Iron Stores and Serum Transferrin Receptor Levels During Recombinant Human Erythropoietin . . . ”.
Arthrits & Rheumatism, vol. 38, No. 9, Sep. 1995, p. S288, H.R.M. Peeters et al., “Effect of Recombinant-Human Erythropoietin on Anaemia and Disease Activity in Patients . . . ”.
Ewoldt G. R.
Roche Diagnostics GmbH
TraskBritt
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