Polynucleotide encoding the hOT7T175 G protein coupled receptor

Details Polynucleotide encoding the hOT7T175 G protein coupled receptor Polynucleotide encoding the hOT7T175 G protein coupled receptor

2008-01-01

2008-01-01

Bunner, Bridget E. (Department: 1647)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S235100, C435S320100, C536S023100, C530S350000

Reexamination Certificate

active

07314754

ABSTRACT:
The present invention relates to a polynucleotide encoding a human brain-derived G protein coupled receptor protein. The human brain-derived G protein coupled receptor protein is useful: (1) for determination of a ligand to the receptor protein, (2) as an agent for the prevention and/or treatment of diseases associated with dysfunction of the receptor protein, (3) as a genetic diagnostic agent, (4) for quantification of a ligand to the receptor protein, (5) for screening of a compound that alters the binding property between the receptor protein and a ligand, (6) as an agent for the prevention and/or treatment of various diseases, comprising a compound that alters the binding property between the receptor protein and a ligand, (7) for quantification of the receptor protein, (8) for neutralization by antibodies to the receptor protein and (9) for preparation of a non-human animal bearing the DNA encoding the receptor protein.

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