Acoustic ejection into small openings

Radiant energy – Ionic separation or analysis – With sample supply means

Reexamination Certificate

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C422S105000, C422S063000, C435S030000, C436S180000, C073S864000, C073S864810

Reexamination Certificate

active

07405395

ABSTRACT:
Provided is a method of transporting fluid which involves acoustic ejection into a small opening. The opening may be, for example, the inlet opening of a sample vessel. Alternatively, it may be an opening in a microfluidic device. The ejection is typically, but not necessarily carried out through the application of focused acoustic energy. The fluid being transported typically comprises a moiety of interest for analysis or further processing, which may be a biomolecule. The volumes of transported fluid may be in the nanoliter or picoliter range. Ejection may occur from very small volumes and the ejected droplet may carry away a significant fraction of the volume from which ejection occurs.

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