Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-07-22
2008-07-22
Saeed, Kamal (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S326000
Reexamination Certificate
active
07402676
ABSTRACT:
This invention relates to a compound of Formula I, a method for its preparation and its use in the preparation of a compound of Formula IIwherein R1, R2, R3, X and n are as defined in the disclosure.This invention also discloses preparation of compounds of Formula IIIwherein R1, R2, R6, R7, R8and n are as defined in the disclosure.Also disclosed are certain intermediates of Formula 4 for the preparation of compounds of Formula Iwherein X is N and R2, R3and n are as defined in the disclosure.
REFERENCES:
patent: 3153654 (1964-10-01), Ficken et al.
patent: 4888340 (1989-12-01), Neh et al.
patent: 5945541 (1999-08-01), Sohn et al.
patent: 6747047 (2004-06-01), Lahm et al.
patent: 2003/0229050 (2003-12-01), Lahm et al.
patent: 2004/0142984 (2004-07-01), Lahm et al.
patent: 2004/0171649 (2004-09-01), Annis et al.
patent: 2004/0198984 (2004-10-01), Lahm et al.
patent: 0 333 131 (1989-09-01), None
patent: 204790 (1988-05-01), None
patent: 9-17 6124 (1997-07-01), None
patent: 9-31 6056 (1997-12-01), None
patent: 9 202 076 (1994-06-01), None
patent: WO 01 70671 (2001-09-01), None
patent: WO 03/016 282 (2003-02-01), None
patent: WO 03/015519 (2003-02-01), None
Cugola et al., caplus an 1995:143635.
F. Foti et. al., Tetrahedron Letters, First Synthesis of a Bromonitrilmine. Direct Formation of 3-Bromopyrazole Derivatives, 1999, vol. 40, pp. 2605.
Donald J.P. Pinto et. al.. Discovery of 1-[3-(Aminomethyl)Phenyl)-N[3-Fluoro-2′-(Methylsulfonyl)-[1,1′-Biphenyl]-4-YL) -3-(Trifluoromethyl)-1H-Pyrazole-5-Carboxamide (DPC423), A Highly Potent, Selective, and Orally Biovailable inhibitor of Blood Coagulation Factor XA1, J. Med. Chem., 2001. vol. 44, pp. 566-578.
M.V. Gorelik et. al., “Structure and Properties of . . .”, Journal of Organic Chemistry U.S.S.R. (English) 1985, vol. 21, pp. 773-781.
K.K. Bach et. al., “1,3-Dipolar Cycloadditions of . . .”, Tetrahedron, 1994, vol. 50 (25), pp. 7543-7656.
J.P. Chupp, “New Regional Isomers of . . .”. J. Heterocyclic Chem., 1994, vol. 31, pp. 1377-1380.
E.I. Du Pont de Nemours and Company
Loewe Sun Jae Y
Saeed Kamal
LandOfFree
Substituted dihydro 3-halo-1H-pyrazole-5-carboxylates their... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted dihydro 3-halo-1H-pyrazole-5-carboxylates their..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted dihydro 3-halo-1H-pyrazole-5-carboxylates their... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2799851