Treatment of hyperproliferative conditions of body surfaces

Details Treatment of hyperproliferative conditions of body surfaces Treatment of hyperproliferative conditions of body surfaces

2008-03-18

2008-03-18

Peselev, Elli (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S006400

Reexamination Certificate

active

07345023

ABSTRACT:
The present invention relates to pharmaceutical formulations comprising an anthracycline and the uses thereof for treatment of clinical conditions of body surfaces such as skin and mucosal membranes, wherein abnormal cell differentiation and/or hyperproliferation is a primary factor of the pathogenesis. In particular the invention relates to treatment of psoriasis, and preferably to treatment of psoriasis with valrubicin topically applied.

REFERENCES:
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Onrust, et al., “Valrubicin”,Drugs&Aging, vol. 15 (1), pp. 69-75, Jul. 1999.
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Dantchev, et al., “Ultrastructural Study of the Cardiotoxicity and Light-Microscopic Findings of the Skin After Treatment of Golden Hamsters with Seven Different Anthracyclines”,Recent Results Cancer Res., vol. 74, pp. 223-249, 1980.
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Anthra Pharmaceuticals, Inc., “Valstar™ (valrubicin) Sterile Solution for Intravesical Instillation”, FDA NDA 20,892, pp. 1-11, 2001.

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