Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-03-25
2008-03-25
Anderson, Rebecca (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S428000, C514S429000, C548S530000, C548S566000, C548S570000, C548S577000
Reexamination Certificate
active
07348356
ABSTRACT:
Disclosed are compounds of formula (I)which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease and pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the beta-secretase enzyme is involved.
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Moore et al., “Difluoro Ketone Peptidomimetics Suggest a Large S1 Pocket for Alzeheimer's gamma-Secretase: Implications for Inhibitor Design,” J. Med. Chem., vol. 43, pp. 3434-3442 (2000).
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Coburn Craig A.
Stachel Shawn J.
Vacca Joseph P.
Anderson Rebecca
Chu Yong
Krovatin William
Merck & Co. , Inc.
Todaro John C.
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