Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2008-07-15
2008-07-15
Mondesi, Robert B. (Department: 1656)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C514S002600, C530S300000
Reexamination Certificate
active
07399831
ABSTRACT:
The present invention is directed to methodology that allows a variety of compounds to be attached to self-assembling peptides using biotin/streptavidin linkages. The peptides can be used to form a biologically compatible membrane that promotes the growth and differentiation of cells. The attached therapeutic agents can be used to promote this process and the gel along with the growing cells can be implanted at a site in vivo where tissue repair is needed. Alternatively, membranes can be used for culturing cells in vitro or can be used for delivering drugs in vivo in the absence of seeded cells.
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Davis Michael E.
Lee Richard T.
Desai Anand U
Law Offices of Michael A. Sanzo, LLC
Mondesi Robert B.
Sanzo Michael A.
The Brigham and Women's Hospital, Inc.
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