Indole derivatives comprising an acetylene group

Details Indole derivatives comprising an acetylene group Indole derivatives comprising an acetylene group

2008-07-29

2008-07-29

Shameem, Golam M (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S469000, C548S509000, C548S510000

Reexamination Certificate

active

07405236

ABSTRACT:
This invention is directed to compounds of the formula (I):wherein one of R6, R7, R8and R9isand X, R1to R12, m, n and o are as defined in the description, and pharmaceutically acceptable salts and/or esters thereof. The invention is also directed to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.

REFERENCES:
patent: 4378368 (1983-03-01), Cassady et al.
patent: 6890947 (2005-05-01), Binggeli et al.
patent: 6995263 (2006-02-01), Ackermann et al.
patent: 7253192 (2007-08-01), Ackermann et al.
patent: 7265149 (2007-09-01), Ackermann et al.
patent: 1380562 (2004-01-01), None
patent: 1394147 (2004-03-01), None
patent: WO 03/074051 (2003-09-01), None
patent: WO 2004/063190 (2004-07-01), None
Oliver et al; Proc Nat Acad Sci USA 2001; 98: 5306-11.
Guerre-Millo et al; J Biol Chem 2000; 275: 16638-16642.
Natchus, Michael G, et. al.,Journal of Medicinal Chemistry (2001), 44(7), 1060-1071.
M. Matsumoto, N. Watanabe,Heterocycles1987, 26, 913-916.
E. Piers, V. B. Haarstadt, R. J. Cushley, R. K. Brown,Canadian Journal of Chemistry1962, 40, 511-517.
J. Labeled Compounds & Radiopharmaceuticals 43(7), 683-691, (2000).
Tetrahedron Letters 43(42), 7617-7619(2002).
Belostotskii, Anatoly M., Hassner, A.,Tetrahedron Lett. 1994, 35(28), 5075-6.
Loibner, H., Pruckner, A., Stuetz, A.,Tetrahedron Lett. 1984, 25, 2535-2536.
Stara, Irena G, et. al, . Chem. Commun. (1999), 64(4), 649-672.
Thorand, Stephan; Krause, Norbert Journal of Organic Chemistry (1998), 63(23), 8551-8553.

Affiliated with

Also associated with

Rating

Indole derivatives comprising an acetylene group does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Indole derivatives comprising an acetylene group, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Indole derivatives comprising an acetylene group will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2787883