Certain 2-substituted cephalosporins

Details Certain 2-substituted cephalosporins Certain 2-substituted cephalosporins

1974-08-21

1978-07-04

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 22, 544 23, 544 24, 544 25, 544 28, 544 29, 544 30, C07D50120

Patent

active

040989992

ABSTRACT:
Disclosed herein are novel analogs of cephalosporins. They differ from prior art compounds in that they are substituted in the 2-position and can be prepared by reacting known cephalosporins with an active source of halogen to form a 2-halogenated intermediate. Substitution of the thus formed intermediate can be accomplished with various substitutents. The compounds of this invention are useful antimicrobial and antibacterial agents.

REFERENCES:
patent: 3578660 (1971-05-01), Cooper
patent: 3660395 (1972-05-01), Wright et al.
patent: 3923795 (1975-12-01), Spry

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