Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Reexamination Certificate
2008-04-08
2008-04-08
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
C435S146000, C435S189000, C435S193000, C435S069100, C435S252330, C536S023200
Reexamination Certificate
active
07354746
ABSTRACT:
The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for producing optically active monatin, and an aldolase which can be used in these methods. As such, the present invention enables the synthesis of 4-(Indole-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid with high optical purity, which is useful as an intermediate in the synthesis of optically active monatin, from indole pyruvic acid and pyruvic acid (or oxaloacetic acid).
REFERENCES:
patent: 2006/0003426 (2006-01-01), Sugiyama et al.
patent: WO2006093322 (2006-08-01), None
U.S. Appl. No. 11/276,614, filed Mar. 8, 2006, Suzuki et al.
U.S. Appl. No. 11/532,618, filed Sep. 18, 2006, Suzuki et al.
Hara Seiichi
Suzuki Shunichi
Taba Toshiki
Takakura Yasuaki
Ajinomoto Co. Inc.
Cermak Shelly Guest
Cermak Kenealy & Vaidya LLP
Meah Md. Younus
Prouty Rebecca E.
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