Method for producing monatin

Details Method for producing monatin Method for producing monatin

2008-07-08

2008-07-08

Saeed, Kamal A (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07396941

ABSTRACT:
By simultaneously carrying out an isomerization reaction at position 2 of monatin in different configurations at positions 2 and 4 in the presence of an aldehyde under a condition of pH 4 to 11 in a mixture solvent of water and an organic solvent, and the crystallization of monatin in the same configurations at positions 2 and 4 or a salt thereof, monatin useful as a sweetener, particularly optically active monatin can efficiently be produced.

REFERENCES:
patent: 7064219 (2006-06-01), Kawahara et al.
patent: 2005/0020508 (2005-01-01), Amino et al.
patent: 2005/0137246 (2005-06-01), Amino et al.
patent: 2005/0272939 (2005-12-01), Amino et al.
patent: 2004-222657 (2004-08-01), None
patent: 03/059865 (2003-07-01), None
Jerry March, Advanced Organic Chemistry, 4thedition, 1992, p. 896-7.
Ebbers et al. Tetrahedron, 1997, vol. 53, 28, p. 9417-9476, (disclosed in IDS).
Nakamura et al., Letters, 2000, vol. 2, 19, p. 2967-70, (disclosed in IDS).
Nakamura, Kozo, et al., “Total Synthesis of Montain,” Letters, vol. 2, No. 19, Jun. 23, 2000, pp. 2967-2970.
Holzapfel, C. W., “A Simple Cycloaddition Approach to A Racemate of the Natural Sweetner Monatin,” Synthetic Communications, vol. 24, No. 22, 1994, pp. 3197-3211.
Ebbers, E. J., et al., “Controlled Racemization of Optically Active Organic Compounds: Prospects for Asymmetric Transformation,” Tetrahedron, vol. 53, No. 28, 1997, pp. 9417-9476.
De Jesus Oliveria, D., et al., “Diastereoselective Formation Of A Quaternary Center In A Pyroglutamate Derivative. Formal Syntheis Of Monatin,” Tetrahedron Letters, vol. 42, 2001, pp. 6793-6796.
U.S. Appl. No. 11/627,700, filed Jan. 26, 2007, Amino, et al.
U.S. Appl. No. 11/505,997, filed Aug. 18, 2006, Mori, et al.
Yamada, S., et al., “Method for the Racemization of Optically Active Amino Acids,” J. Org. Chem., vol. 48, No. 6, 1983, pp. 843-846.

Affiliated with

Also associated with

Rating

Method for producing monatin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for producing monatin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for producing monatin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2782256