Radiant energy – Ionic separation or analysis
Reexamination Certificate
2008-04-01
2008-04-01
Berman, Jack I. (Department: 2881)
Radiant energy
Ionic separation or analysis
C250S282000, C250S283000, C250S284000, C250S293000, C250S296000
Reexamination Certificate
active
07351955
ABSTRACT:
A MALDI mass spectrometer includes a radiation source, such as a gas or solid state laser, that emits a beam of radiation (typically in the UV or IR wavelengths) directed along the central axis of a linear ion trap in which analyte ions and matrix cluster ions are confined. The radiation beam has a wavelength that is strongly absorbed by the matrix cluster ions. The absorption of radiation by the matrix cluster ions produces dissociation of the matrix cluster ion into fragments having mass-to-charge ratios that lie below a mass-to-charge ratio range of interest. Thus, chemical noise associated with matrix cluster ions is reduced or eliminated.
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Berman Jack I.
Katz Charles B.
Logie Michael J
Thermo Finnigan LLC
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