Resistance-repellent retroviral protease inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C549S464000

Reexamination Certificate

active

07378441

ABSTRACT:
Resistance-repellent and multidrug resistant retroviral protease inhibitors are provided. Pharmaceutical composition comprising such compounds, and methods of using such compounds to treat HIV infections in mammals, are also provided.

REFERENCES:
patent: 6534493 (2003-03-01), Vazquez et al.
patent: 6613743 (2003-09-01), Hale et al.
patent: WO 03/049746 (2003-06-01), None
Dorsey et al., J. Med. Chem. 2000, v 43, p 3386-3399.
Turner et al., Curr. Med. Chem. 2002, v 1, p 141-162 “HIV Protease Inhibitors—The Next Generation”.

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