Methods for diagnosis and prognosis of cancer

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S350000

Reexamination Certificate

active

07993863

ABSTRACT:
We have discovered a protein in humans, herein referred to as collagen like gene (CLG) product (SEQ ID NOS: 12 and 13), that is expressed in human prostate cancer and breast cancer cell lines but not in normal adult, placenta, lung, liver, skeletal muscle, kidney or pancreas tissues. We have also discovered that the level of CLG mRNA expression correlates positively with the metastatic potential of the cancer cell lines tested.

REFERENCES:
patent: 2003/0224982 (2003-12-01), Li et al.
patent: 2004/0250304 (2004-12-01), Iwatsubo et al.
patent: WO 00/58473 (2000-10-01), None
patent: 01/58943 (2001-08-01), None
Skolnick et al. (Trends in Biotech., 18(1):34-39, 2000).
Tockman et al, Cancer Research vol. 52 p. 2711s (1992).
Blood CH, Zetter BR, Tumor interactions with the vasculature: angiogenesis and tumor metastasis,Biochim Biophys Acta. 1990;1032(1):89-118.
Fidler IJ, Gersten DM, Hart IR, The biology of cancer invasion and metastasis,Adv Cancer Res1978;28:149-250.
Fidler IJ, Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis,Cancer Metastasis Rev. 1986;5(1):29-49.
Haemmerli G, Sträuli P, in vitro motility of cells from human epidermoid carcinomas. A study by phase-contrast and reflection-contrast cinematography,Int J Cancer. 1981;27(5):603-10.
Hosaka S, Suzuki M, Goto M, Sato H, Motility of rat ascites hepatoma cells, with reference to malignant characteristics in cancer metastasis, Gann. Apr. 1978;69(2):273-6.
Liotta LA, Stracke ML, Tumor invasion and metastases: biochemical mechanisms,Cancer Treat Res. 1988;40:223-38.
Nicolson GL, Cancer metastasis: tumor cell and host organ properties important in metastasis to specific secondary sites,Biochim Biophys Acta. 1988;948(2):175-224.
Zetter BR, The cellular basis of site-specific tumor metastasis, N Engl J Med. 1990;322(9):605-12.
International Search Report for PCT/US03/08100 mailed on Oct. 20, 2003.
Breslin, P.W. et al. Characterization of deletions in a new human collagen-like gene. American Journal of Human Genetics. Oct. 24-28, 1995, vol. 57, No. 4 SUPPL., p. A141, Abstract No. 796.
Banyard et al., Collagen XXIII expression is associated with prostate cancer recurrence and distant metastases. Clin Cancer Res. May 1, 2007;13(9):2634-42.
Banyard et al., Type XXIII collagen, a new transmembrane collagen identified in metastatic tumor cells. J Biol Chem. Jun 6, 2003;278(23):20989-94. Epub Mar 18, 2003.
Gordon et al., Cloning of a new collagen, type XXIII, expressed in cornea. IOVS. Mar. 15, 2000;41(4): Abst 3997.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods for diagnosis and prognosis of cancer does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for diagnosis and prognosis of cancer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for diagnosis and prognosis of cancer will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2769938

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.