Diclofenac sodium oral pharmaceutical

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form

Reexamination Certificate

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Details

C424S451000, C514S566000, C514S567000

Reexamination Certificate

active

07378102

ABSTRACT:
The present invention relates to a diclofenac sodium oral pharmaceutical containing diclofenac sodium, a nonionic surfactant, a cholic acid derivative as an absorption promoting agent, and a glycerin or a glycol.The oral pharmaceutical has a rapid-acting effect and a good internal absorption even under non-fasting condition. Further, the pharmaceutical can be processed in a hard capsule pharmaceutical by filling it in a hard capsule as such, and has an excellent internal absorption under non-fasting condition, similarly to suppositories.

REFERENCES:
patent: 4944949 (1990-07-01), Story et al.
patent: 5785976 (1998-07-01), Westesen et al.
patent: 5789244 (1998-08-01), Heidrun et al.
patent: A 63-277617 (1988-11-01), None
patent: A 7-508013 (1995-09-01), None
patent: A 8-507515 (1996-08-01), None
patent: A 10-152431 (1998-06-01), None
patent: A 2002-509103 (2002-03-01), None
patent: WO 94/20072 (1994-09-01), None
patent: WO 00/72827 (2000-12-01), None
Gennaro, Remington's Pharmaceutical Sciences, 1990, 18th Ed., p. 1658.
Fini et al., European Journal of Pharmaceutical Sciences, 1996;4(4):231-238.
Remington's Pharmaceutical Sciences, 18th ed., 1990, pp. 207-208.

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