Process for producing HMG-CoA reductase inhibitor

Details Process for producing HMG-CoA reductase inhibitor Process for producing HMG-CoA reductase inhibitor

2011-03-01

2011-03-01

Ramirez, Delia M (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

C435S135000, C435S136000, C435S142000, C435S146000, C435S148000, C435S156000, C435S025000, C435S125000, C435S252300, C435S252310, C435S252320, C435S252330, C435S320100, C435S325000, C435S069100, C435S252350, C530S350000, C536S023200

Reexamination Certificate

active

07897370

ABSTRACT:
The present invention relates to a protein derived from a microorganism belonging to the genusBacillus, which has an activity of hydroxylating a compound represented by the formula (I-a):wherein R1represents a hydrogen atom, a substituted or unsubstituted alkyl, or an alkali metal, and R2represents a substituted or unsubstituted alkyl or a substituted or unsubstituted aryl,or a ring-closed lactone form thereof;a DNA encoding the protein; and a recombinant DNA comprising the DNA.

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