Methods and compositions for treating cancer

Details Methods and compositions for treating cancer Methods and compositions for treating cancer

2008-05-13

2008-05-13

Crane, L. E. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

Reexamination Certificate

active

07371776

ABSTRACT:
This invention relates to methods of inducing dephosphorylation of a hyperphosphorylated cell cycle regulatory protein in a tumor cell in which hyperphosphorylation of said protein contributed to cell transformation, the method comprising contacting the tumor cell with a procyanidin oligomer of five monomeric units connected via a C-4→C-8 linkage. Examples of such compounds are [EC-(4β→8)]4-EC, and [EC-(4β→8)]3-EC-(4β→8)-C, wherein EC is epicatcchin and C is catechin.

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