Therapeutic compositions (II)

Details Therapeutic compositions (II) Therapeutic compositions (II)

2008-04-01

2008-04-01

Kwon, Brian (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

Reexamination Certificate

active

07351736

ABSTRACT:
Method of producing a physiologically acceptable ketosis such as to treat a patient in need of therapy for one or more of Amylotrophic lateral sclerosis, Free Radical disease, Heart failure and Duchenne's muscular dystrophy by oral administration to the patient of a cyclic oligomer of formula (I)where n is an integer of 1 or more or a complex thereof with one or more cations or a salt thereof, wherein the physiologically acceptable ketosis is characterized by blood levels of (R)-3-hydroxybutyrate of from 0.5 to 20 mM.

REFERENCES:
patent: 5286842 (1994-02-01), Kimura
patent: 6136862 (2000-10-01), Hiraide et al.
patent: 6207217 (2001-03-01), Peoples et al.
patent: 6323237 (2001-11-01), Veech
patent: 6380244 (2002-04-01), Martin et al.
patent: 2004/0266872 (2004-12-01), Veech
patent: 0780123 (1997-06-01), None
patent: 00/04895 (2000-02-01), None
“Heart Failure Ketosis”, Lommi et al., Journal of Internal Medicine, 1997, vol. 242, pp. 231-238.
“Ketosis and Cardiac Failure: Common Signs of a Single Condition”, Diltoer et al., European Journal of Emergency Medicine, abstract, 11(3):172-175, 2004.

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