Spiro-isoquinoline-pyrrolidines and analogs thereof useful as al

Details Spiro-isoquinoline-pyrrolidines and analogs thereof useful as al Spiro-isoquinoline-pyrrolidines and analogs thereof useful as al

1991-04-04

1992-03-03

Shen, Cecilia

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546142, 560 55, 560 56, 560 80, 560 81, 560 82, 560 96, C07D41314, C07D41714, C07D41706

Patent

active

050934961

ABSTRACT:
This invention relates to spiro-isoquinoline-pyrrolidines and their pharmaceutically acceptable salts thereof, to processes for their preparation, to methods for using the compounds, and to pharmaceutical preparations thereof. The compounds have pharmaceutical properties which render them beneificial for the prevention or treatment of diabetes mellitus associated complications.

REFERENCES:
patent: 4861792 (1989-08-01), Kurons
patent: 4927831 (1990-05-01), Malamas
Malen et al., Chem. Abst. 100:121065s (1984).
Brittain Chem. Abst. 105: 4267x (1986).
Belgaonkar et al., CA89-436990 (1978).
Bruggink et al., CA84-43558q (1976).

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